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DSP-4 hydrochloride

CAS No. 40616-75-9

DSP-4 hydrochloride( Neurotoxin DSP 4 (hydrochloride) )

Catalog No. M22486 CAS No. 40616-75-9

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DSP-4 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).
  • Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats.
  • In Vitro
    ——
  • In Vivo
    Animal Model:rats Dosage:50 mg/kg Administration:intraperitoneal , single Result:Not visualized large projection neurons and the fibers of the LC.
  • Synonyms
    Neurotoxin DSP 4 (hydrochloride)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40616-75-9
  • Formula Weight
    313.06
  • Molecular Formula
    C11H16BrCl2N
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (399.28 mM; Need ultrasonic)
  • SMILES
    Cl.CCN(CCCl)Cc1ccccc1Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
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