DSP-4 hydrochloride

CAS No. 40616-75-9

DSP-4 hydrochloride( Neurotoxin DSP 4 (hydrochloride) )

Catalog No. M22486 CAS No. 40616-75-9

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 In Stock
10MG 58 In Stock
50MG 146 In Stock
100MG 225 In Stock
200MG 337 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    DSP-4 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).
  • Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats.
  • In Vitro
    ——
  • In Vivo
    Animal Model:rats Dosage:50 mg/kg Administration:intraperitoneal , single Result:Not visualized large projection neurons and the fibers of the LC.
  • Synonyms
    Neurotoxin DSP 4 (hydrochloride)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40616-75-9
  • Formula Weight
    313.06
  • Molecular Formula
    C11H16BrCl2N
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (399.28 mM; Need ultrasonic)
  • SMILES
    Cl.CCN(CCCl)Cc1ccccc1Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
molnova catalog
related products
  • N3-C5-NHS ester

    N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

  • Cochinchinenin A

    Cochinchinenin A is the material basis for the analgesic effect of Dragons Blood.

  • SHMT-IN-2

    SHMT-IN-2 (compound 2) is a specific human SHMT1/2 small molecule inhibitor that acts on SHMT1 (IC50: 13 nM) and SHMT2 (IC50: 66 nM). SHMT-IN-2 inhibits the growth of many human cancer cells and is sensitive to B-cell lymphoma.